덴탈타입실리카, 토코페롤아세테이트, 불화나트륨 및 피로인산나트륨 배합 세치제가 치아표면 탈회 및 치아밀도 감소 억제에 미치는 영향
The effect of dentifrice including dental type silica, tocopherol acetate, sodium fluoride and sodium pyrophosphate on mineral density in enamel
정호기, 정선영, 안용수, 조자원,
소속 상세정보
정호기 ( Jung Ho-Ki ) - Dankook University College of Dentistry Department of Preventive Dentistry
정선영 ( Chung Sun-Young ) - Dankook University College of Dentistry Department of Preventive Dentistry
안용수 ( Ahn Yong-Su ) - Dankook University College of Dentistry Department of Preventive Dentistry
조자원 ( Cho Ja-Won ) - Dankook University College of Dentistry Department of Preventive Dentistry
Abstract
Objectives: In this study, we aimed to investigate the preventive and protective effects of new dentifrice containing dental type silica, tocopheryl acetate, fluorides, and sodium pyrophosphate on the mineral density of teeth and demineralization of tooth surfaces.
Methods: A total of 119 bovine teeth pre-treated with the new dentifrice at three different concentrations for the experiment were randomly allocated into two control (DW and PW) and one experimental (EC) groups. The enamel surface of all bovine teeth were demineralized using an artificial demineralization solution. The dentifrice was diluted with distilled water (DW) at 1:1, 1:2, and 1:3 ratios. The samples were treated with the demineralization solution for 4 h after treatment with the supernatants of each diluted dentifrice for 30 min, and this procedure was repeated 3 times over a period of 24 h. The samples were examined using micro-CT to determine the amount of reduced bone mineral density (BMD) comparing the control and experimental dentifrices. The surface changes of the samples were also examined using the scanning electron microscope (SEM).
Results: The average BMD of the bovine enamel surface between the treated and non-treated area with the dimineralization solution was significantly different in the control, DW, PW 1:1, PW 1:2, and PW 1:3 groups. However, there was no significant difference observed in the experimental groups, including EC 1:1, EC 1:2, and EC 1:3. The average BMD of the dimineralized surfaces based on the results of the 7 groups was significantly higher in every EC group when compared to the DW and three PW groups.
Conclusions: The new dentifrice containing dental type silica, tocopheryl acetate, fluorides, and sodium pyrophosphate is effective in inhibiting the decrease in BMD and demineralization of enamel surface, which was observed when the new dentifrice and demineralization solution was repeatedly applied to the samples for 24 h.
키워드
Dentifrices; Sodium fluoride; Sodium pyrophosphate
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